• Multi Species
  • Potent Inhibitor of PDE7
  • Indices apoptosis
  • Cell permeable

BRL-50481 is a potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM.  Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B. Increases mineralization in osteoblasts differentiated from hMSC. Cell permeable.

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