IOX1

Features

  • Multi Species
  • Inhibitor of Jumonji HDMs
  • Broad spectrum 2-oxoglutarate oxygenase inhibitor
  • Cell Permeable

Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. Is a broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Cell permeable

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