Xanthohumol

Features

  • Impairs prostate cancer cell growth
  • Inhibits the function of VCP
  • Cell permeable

Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II). Impairs prostate cancer cell growth and proliferation. Cell permeable.

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