Zebrafish Id1 Rbt pAb, Protein A purified

Features

  • Rabbit Antibody to a peptide from the C-terminal end of Id1 (Zebrafish)
  • Genbank accession# NP_571320.1
  • Reacts with zebrafish Id1

The Id proteins (Inhibitors of DNA Binding/Differentiation) represent a family of dominant negative regulators of the basic helix-loop-helix transcription factors whose activities result in delayed cell differentiation and prolonged proliferation. The down-regulation of Id1 is necessary for differentiation to proceed in many cell lineages. Id1-deficient hematopoietic stem cells (HSCs) show increased cell cycling, but fail to efficiently self- renew.  Id1 has been implicated in the maintenance of HSCs via its role in the cell cycle regulation.

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