Connecting the Dots in Diabetes Research
November marks Diabetes Awareness Month, a time to recognize the scale of the disease and the researchers working to understand it. More than 537 million adults worldwide live with diabetes, according to the International Diabetes Federation. So, check out some important new findings.
The Search for Smarter Treatments
Managing diabetes is more than keeping glucose levels in range. It’s a complex balance of hormones, cell signaling, and metabolism. While insulin therapy remains an effective treatment, it’s not ideal for every patient. Oral medications also exist, but many bring unwanted side effects or lose effectiveness over time.
That’s why research continues to focus on new therapeutic targets that could support insulin secretion and regulate glucose through natural pathways in the body.
GPR119 and the Role of cAMP
One promising avenue of research focuses on G-protein-coupled receptors (GPRs), particularly GPR119, which helps regulate insulin and hormone release in pancreatic and gut cells. A study published in Bioorganic & Medicinal Chemistry used Arbor Assays’ DetectX® Cyclic AMP Direct ELISA Kit (K019-H) to measure cAMP levels as part of work developing a potential new treatment option.
The compound showed improved activation potency and efficacy in both cell and animal models, pointing to new possibilities for future drug development.
You can read more about this research on the Arbor Assays website here.
Measuring What Matters and The Tools Behind the Data
Reliable assays make it possible to connect molecular signals with clinical outcomes and bridge the gap between lab discovery and patient care.
Insulin as the Cornerstone of Glucose Regulation
Insulin, a 51-amino acid peptide secreted by pancreatic β-cells, plays a central role in glucose metabolism. It promotes glucose uptake and suppresses gluconeogenesis, maintaining steady blood sugar levels. When insulin function falters, hyperglycemia and diabetes can follow.
The DetectX® Insulin ELISA Kit provides researchers with a straightforward way to measure insulin concentrations in biological samples. It supports studies on diabetes, insulin resistance, and metabolic syndrome, helping clarify how insulin drives energy balance throughout the body.
Glucose is the Energy Currency
Glucose is the body’s main fuel source, powering muscles, the brain, and countless cellular processes. Too little glucose can cause seizures or neuroglycopenia, while too much can lead to long-term complications like β-cell dysfunction and organ damage.
The DetectX® Glucose Colorimetric Detection Kit gives researchers a precise and efficient way to measure glucose in serum, plasma, urine, and tissue culture media. Its accuracy supports studies in metabolism, diabetes, neurobiology, and more.
Hemoglobin Can be the Oxygen Connection
Hemoglobin carries oxygen through the bloodstream, ensuring cells get the energy they need to function. Shifts in hemoglobin levels can signal anemia, erythrocytosis, or other health concerns. In diabetes research, it also provides insight into how oxygen transport and metabolism are affected by disease.
The DetectX® Hemoglobin Colorimetric Detection Kit enables accurate, reproducible, and quantitative hemoglobin measurement for research and clinical applications. From metabolic studies to sports physiology and nutrition, this assay helps scientists track how the body adapts under different physiological demands.
From Benchwork to Better Care
Each of these tools, whether measuring cAMP, insulin, glucose, or hemoglobin, helps researchers better understand the biology driving diabetes. The more precise the data, the clearer the path toward treatments that improve lives.
This Diabetes Awareness Month, Arbor Assays celebrates the researchers working every day to turn complex science into actionable knowledge.
Featured Products
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In StockCyclic AMP Direct ELISA Kit
$446.00 – $1,783.00The DetectX® Cyclic AMP (cAMP) Direct ELISA Kits quantitatively measure cAMP present in a variety of samples.
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Limited AvailabilityInsulin ELISA Kit
$605.00The DetectX® Insulin ELISA Kit is designed to quantitatively measure insulin present in a variety of samples and tissue culture media.
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In StockGlucose Colorimetric Detection Kit
$425.00The DetectX® Glucose Colorimetric Detection Kit quantitatively measures glucose in a variety of samples.
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In StockHemoglobin Colorimetric Detection Kit
$338.00The DetectX® Hemoglobin Colorimetric Detection Kit uses a single reaction solution to measure Hemoglobin in whole blood and RBCs without dangerous chemicals or light sensitivity.
