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Garcinol is an inhibitor of the histone acetyltransferases (HATs) p300 and PCAF with IC50 of 7 and 5 uM, respectively….

FK-866 is a selective inhibitor of the nicotinamide pathway dependent NAD+ synthesis, causing NAD+ depletion. Highly specific, non-competitive inhibitor of…

EX-527 is a cell-permeable, selective inhibitor of SIRT1 (IC50 = 98 nM in vivo, 38nM in vitro) that does not…

DMXAA is a STING (Stimulator of Interferon Genes) agonist selective for mouse STING.

Cytosine analog, that when incorporated into DNA, acts as a suicide substrate for DNA methyltransferase. Inhibits DNA methyltransferase and results…

A reversible, cell-permeable pyrazolone p300/CBP HAT inhibitor (Ki = 400 nM), which competes with acetyl-CoA for the p300 Lys-CoA binding…

Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1…

Inhibition of histone deacetylase (HDAC) enzymes by compounds such as trichostatin A can have wide ranging effects in cancer, cell…

Potent inhibitor of histone deacetylase (HDAC) activity and proliferation. Induces cell cycle arrest at the G1 phase. At 100 nM…

Incorporates into DNA, forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves…

AbX™ Trimethyl Lys4 Histone H3 Rabbit Polyclonal Antibody for Western blotting and ChIP.

AbX^™ PGE₂ Mouse Monoclonal Antibody is produced as a carrier protein free solution of Protein G purified antibody.

AbX™ Monomethyl Lys4 Histone H3 Rabbit Polyclonal Antibody for Western blotting and ChIP.

AbX™ LSD Rabbit Polyclonal Antibody for Western blotting and ChIP.

AbX™ Cysteine Mouse Monoclonal is produced as a Protein A purified antibody. It will measure cysteine-protein complexes under non-reducing conditions.