Showing 49–64 of 156 results
FK-866 HCl
FK-866 is a selective inhibitor of the nicotinamide pathway dependent NAD+ synthesis, causing NAD+ depletion. Highly specific, non-competitive inhibitor of…
Specifications
Pricing
Features
Specific inhibitor of NAMPT
Indirect inhibitor of SIRT1
Causes gradual NAD+ depletion
P006-5MG FK-866 HCl, 5 mg $ 171.00
P006-25MG FK-866 HCl, 25 mg $ 531.00
EX-527
EX-527 is a cell-permeable, selective inhibitor of SIRT1 (IC50 = 98 nM in vivo, 38nM in vitro) that does not…
Specifications
Pricing
Features
Selective SIRT1 inhibitor
Does not inhibit HDACs
Inhibitor of SIRT1 deacetylation of p53
P005-5MG EX-527, 5 mg $ 106.00
P005-25MG EX-527, 25 mg $ 378.00
DMXAA
DMXAA is a STING (Stimulator of Interferon Genes) agonist selective for mouse STING.
Specifications
Pricing
P024-5MG DMXAA, 5 mg $ 176.00
P024-25MG DMXAA, 25 mg $ 660.00
Decitabine
Cytosine analog, that when incorporated into DNA, acts as a suicide substrate for DNA methyltransferase. Inhibits DNA methyltransferase and results…
Specifications
Pricing
Features
DNA Methyltransferase inhibitor
Hypomethylating agent
Inhibits melanoma cancer cell growth
Storage at 4˚C
P015-10MG Decitabine, 10 mg $ 148.00
P015-50MG Decitabine, 50 mg $ 531.00
C-646
A reversible, cell-permeable pyrazolone p300/CBP HAT inhibitor (Ki = 400 nM), which competes with acetyl-CoA for the p300 Lys-CoA binding…
Specifications
Pricing
Features
p300/CBP HAT inhibitor
Inhibits melanoma cancer cell growth
Less than 10% inhibition of other HATs
Storage at 4°C
P014-5MG C-646, 5 mg $ 130.00
P014-25MG C-646, 25 mg $ 561.00
Features
Potent Inhibitor of PDE7
Induces apoptosis
Cell permeable
Room temperature storage
P020-10MG BRL-50481, 10 mg $ 100.00
P020-50MG BRL-50481, 50 mg $ 425.00
BML-278
Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1…
Specifications
Pricing
Features
Novel SIRT activator
Dihydropyridine scaffold
Arrests cell cycle at G1/S phase
P003-5MG BML-278, 5 mg $ 94.00
P003-25MG BML-278, 25 mg $ 378.00
BML-210
Inhibition of histone deacetylase (HDAC) enzymes by compounds such as trichostatin A can have wide ranging effects in cancer, cell…
Specifications
Pricing
Use
Potent HDAC Inhibitor
Increases A549 acetylated histone levels
Inhibits transcription factor FOXO3 by SIRT
P013-5MG BML-210, 5 mg $ 130.00
P013-25MG BML-210, 25 mg $ 460.00
Apicidin
Potent inhibitor of histone deacetylase (HDAC) activity and proliferation. Induces cell cycle arrest at the G1 phase. At 100 nM…
Specifications
Pricing
Features
Potent HDAC Inhibitor
Blocks Cell Cycle G1
HIV-1 Promoter
P011-1MG Apicidin, 1 mg $ 83.00
P011-5MG Apicidin, 5 mg $ 336.00
5-Azacytidine
Incorporates into DNA, forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves…
Specifications
Pricing
Features
DNA Methyltransferase inhibitor
Blocks cell cycle progression at G1
Induces activation of HIV-1 promoter
P012-50MG 5-Azacytidine, 50 mg $ 30.00
P012-250MG 5-Azacytidine, 250 mg $ 112.00
Use
Western blotting and ChIP
Wide Application
Histone H3 from yeast to mammals
A007-100UL Trimethyl Lys4 Histone H3 Polyclonal Antibody $ 248.00
PGE2 Monoclonal Antibody
AbX™ PGE2 Mouse Monoclonal Antibody is produced as a carrier protein free solution of Protein G purified antibody.
Specifications
Pricing
Features
Mouse Monoclonal
Purified IgG with no carrier protein
A011-50UG PGE2 Monoclonal Antibody $ 625.00
Use
Western blotting and ChIP
Wide Application
Histone H3 from yeast to mammals.
A005-100UL Monomethyl Lys4 Histone H3 Polyclonal Antibody $ 248.00
Use
Western blotting and ChIP
Applications
Reacts with mammalian Lysine Specific Demethylase
Format
Supplied as a PBS solution
Storage Short Term
4°C
Storage Extended
Aliquot and freeze at -20°C
A003-100UL LSD1 Polyclonal Antibody $ 248.00
L-Cysteine Monoclonal Antibody
AbX™ Cysteine Mouse Monoclonal is produced as a Protein A purified antibody. It will measure cysteine-protein complexes under non-reducing conditions.
Specifications
Pricing
Versatile
Western blotting, Immunoassay and Immunoprecipitation
Pure
Supplied in PBS with no carrier protein
Stability
4°C short-term, Aliquot and Freeze -20°C long-term
A002-50UG L-Cysteine Monoclonal Antibody $ 248.00
Histone H3 Polyclonal Antibody
AbX™ Histone H3 Rabbit Polyclonal Antibody for Western blotting and ChIP. It reacts with modified Histone H3 and supplied as a PBS solution.
Specifications
Pricing
Application Includes
Western blotting and ChIP
Wide Application
Histone H3 from Yeast to Mammals
Stability
4°C short-term, Aliquot and Freeze -20°C long-term
A004-100UL Histone H3 Polyclonal Antibody $ 248.00
