cancer

The proto-oncogene SRC phosphorylates cGAS to inhibit an antitumor immune response

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Obesity alters monocyte developmental trajectories to enhance metastasis

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Pharmacological boosting of cGAS activation sensitizes chemotherapy by enhancing antitumor immunity

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Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus

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A G-quadruplex stabilizer, CX-5461 combined with two immune checkpoint inhibitors enhances in vivo therapeutic efficacy by increasing PD-L1 expression in colorectal cancer

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Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin is mediated by targeting the Akt signaling pathway and activating the Hippo signaling pathway

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Systemic delivery of gemcitabine analogue and STAT3 siRNA promotes antitumor immunity against melanoma

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Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells

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Plasma aromatase activity index, gonadotropins and estrone are associated with frailty syndrome in post-menopausal women with breast cancer

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Hypoxia enhances HIF1α transcription activity by upregulating KDM4A and mediating H3K9me3, thus inducing ferroptosis resistance in cervical cancer cells

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The endocrine disruptor compound bisphenol-A (BPA) regulates the intra-tumoral immune microenvironment and increases lung metastasis in an experimental model of breast cancer

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Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling

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