BML-278

P003-5MG BML-278, 5 mg In Stock
$106.05
P003-25MG BML-278, 25 mg In Stock
$426.44

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  • Features Novel SIRT activator
  • Dihydropyridine scaffold
  • Arrests cell cycle at G1/S phase
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Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1 uM for Sirt1, 25 uM for Sirt2, and 50 uM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells.