Specifications

  • Features Potent Inhibitor of PDE7
  • Induces apoptosis
  • Cell permeable
  • Room temperature storage
  • Description

    BRL-50481 is a potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B. Increases mineralization in osteoblasts differentiated from hMSC. Cell permeable.

  • Structure Chemical Compound