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- Features Potent Inhibitor of PDE7
- Induces apoptosis
- Cell permeable
- Room temperature storage
BRL-50481 is a potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B. Increases mineralization in osteoblasts differentiated from hMSC. Cell permeable.