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- Sample Saliva, Urine, Extracted Serum, Extracted Plasma, Fecal Extracts, Tissue Culture Media
- Species Epiandrosterone is identical across species
- Sensitivity 0.120 ng/mL
- Time to Answer 2.5 Hours
- Samples/Kit 40 or 232 in Duplicate
- Stability Liquid 4°C Stable Reagents
- Readout Colorimetric, 450 nm
- Standard Curve
Epiandrosterone is a naturally occurring metabolite of dehydroepiandrosterone (DHEA) found in most mammals and produced via the action of the 5α-reductase enzyme. It is a weak androgen formed primarily in peripheral tissues, released into circulation and ultimately excreted in urine. Epiandrosterone has been shown to inhibit the pentose phosphate pathway (PPP), decreasing intracellular NADPH levels. It also attenuates NO-evoked relaxation of the pulmonary artery. It has been linked to gonadal activity and sexual behavior in males. Epiandrosterone is of interest for cell metabolism, cardiac, and prostate cancer research.