Research Areas

Documentation

Specifications

  • Assay Type Competitive ELISA
  • Sample Types Saliva, Urine, Extracted Serum, Extracted Plasma, Fecal Extracts, Tissue Culture Media
  • Sensitivity 0.120 ng/mL
  • Species Epiandrosterone is identical across species
  • Assay Duration 2.5 Hours
  • Samples/Plate 40 in Duplicate
  • Readout Colorimetric, 450 nm
  • Standard Curve
  • Description

    Epiandrosterone is a naturally occurring metabolite of dehydroepiandrosterone (DHEA) found in most mammals and produced via the action of the 5α-reductase enzyme. It is a weak androgen formed primarily in peripheral tissues, released into circulation and ultimately excreted in urine. Epiandrosterone has been shown to inhibit the pentose phosphate pathway (PPP), decreasing intracellular NADPH levels. It also attenuates NO-evoked relaxation of the pulmonary artery. It has been linked to gonadal activity and sexual behavior in males. Epiandrosterone is of interest for cell metabolism, cardiac, and prostate cancer research.

  • Structure