• Assay Type Competitive ELISA
  • Sample Types Serum, Plasma
  • Sensitivity 2.21 pg/mL
  • Species Estradiol is identical across species
  • Assay Duration 2.5 Hours
  • Samples/Plate 40 in Duplicate
  • Readout Colorimetric, 450 nm
  • Standard Curve
  • Description

    Estradiol (E2, 17β-estradiol, or oestradiol) is the predominant sex hormone present in females. It is also present in males, being produced as an active metabolic product of testosterone. It represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs. Serum estradiol measurements in women reflect primarily the activity of the ovaries. As such, they are useful in the detection of baseline estrogen in women with amenorrhea or menstrual dysfunction and to detect the state of hypoestrogenism and menopause. Furthermore, estrogen monitoring during fertility therapy assesses follicular growth. Estrogen-producing tumors and in precocious puberty samples will demonstrate persistent high levels of estradiol and other estrogens.

  • Structure