Glucose Colorimetric Detection Kit (2 Plates)

Research Areas

Product Protocol Product SDS

Assay Type Detection Kit
Sample Types Serum, Plasma, Urine, Buffers, Tissue Culture Media
Sensitivity 0.413 mg/dL
Species Human
Assay Duration 30 Minutes
Samples/Plate 40 in duplicate
Readout Colorimetric, 560 nm
Standard Curve
Description
Glucose is by far the most common carbohydrate energy source for the cell. It is a monosaccharide, an aldose, a hexose, and a reducing sugar. It is also known as dextrose because it is dextrorotatory (rotates polarized light clockwise). For all biological and molecular events and for multiple cellular functions, energy is essential. Reduced energy levels threaten cellular homeostasis and integrity. Impaired energy metabolism may trigger pro-apoptotic signaling (programmed cell death), oxidative damage, or excitotoxicity and may impede mitochondrial DNA repair.

A serious drop in blood glucose can be characterized by metabolic dysfunction, neuroglycopenia, seizure, and death. A persistent elevation in blood glucose leads to “glucose toxicity.” Glucose toxicity contributes to β-cell dysfunction and the pathology grouped together as complications of diabetes. Estrogen-induced signaling pathways in hippocampal and cortical neurons involve the mitochondria to enhance mitochondrial function and to sustain aerobic glycolysis and citric acid cycle oxidative phosphorylation and ATP generation.

The DetectX^® Glucose Colorimetric Detection Kit quantitatively measures glucose in a variety of samples.

Assay Type Detection Kit
Sample Types Serum, Plasma, Urine, Buffers, Tissue Culture Media
Sensitivity 0.413 mg/dL
Species Human
Assay Duration 30 Minutes
Samples/Plate 40 in duplicate
Readout Colorimetric, 560 nm
Standard Curve
Description
Glucose is by far the most common carbohydrate energy source for the cell. It is a monosaccharide, an aldose, a hexose, and a reducing sugar. It is also known as dextrose because it is dextrorotatory (rotates polarized light clockwise). For all biological and molecular events and for multiple cellular functions, energy is essential. Reduced energy levels threaten cellular homeostasis and integrity. Impaired energy metabolism may trigger pro-apoptotic signaling (programmed cell death), oxidative damage, or excitotoxicity and may impede mitochondrial DNA repair.

A serious drop in blood glucose can be characterized by metabolic dysfunction, neuroglycopenia, seizure, and death. A persistent elevation in blood glucose leads to “glucose toxicity.” Glucose toxicity contributes to β-cell dysfunction and the pathology grouped together as complications of diabetes. Estrogen-induced signaling pathways in hippocampal and cortical neurons involve the mitochondria to enhance mitochondrial function and to sustain aerobic glycolysis and citric acid cycle oxidative phosphorylation and ATP generation.