Specifications

  • Sample Types Serum, Plasma, Urine, Fecal Extracts, Tissue Culture Media
  • Species Progesterone is identical across all species
  • Sensitivity 47.9 pg/mL
  • Time to Answer 2.5 Hours
  • Samples/Kit 39 or 231 in Duplicate
  • Stability Liquid 4ºC stable reagents
  • Readout Colorimetric, 450 nm
  • Standard Curve
  • Description

    Progesterone, also known as P4 (Pregn-4-ene-3,20-dione), is a C21 steroid hormone involved in the female menstrual cycle, gestation and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens and is the major naturally occurring progestogen. Progesterone is an essential regulator of human female reproductive function in the uterus, ovary, mammary gland and brain, and plays important roles in non-reproductive tissues such as the cardiovascular, skeletal, and central nervous systems. Progesterone action is conveyed by two isoforms of the nuclear progesterone receptor (PR), PR-A and PR-B. PR-A and -B are expressed in a variety of normal breast tissue from humans, rats and mice and is also expressed in breast cancer cells. Progesterone also has neurotrophic roles in the peripheral nervous system as it activates the growth and maturation of axons and stimulates the repair and replacement of myelin sheaths in regenerating nerve fibres.

    Available as:
    K025-H1, 1 Strip-Well Plate
    K025-H5, 5 Strip-Well Plate
    K025-H1W, 1 Whole Plate
    K025-H5W, 5 Whole Plate