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- Assay Type Competitive ELISA
- Sample Types Serum, Plasma, Urine, Fecal Extracts, Tissue Culture Media
- Sensitivity 47.9 pg/mL
- Species Progesterone is identical across all species
- Assay Duration 2.5 Hours
- Samples/Plate 39 or 231 in Duplicate
- Readout Colorimetric, 450 nm
- Standard Curve
Progesterone, also known as P4 (Pregn-4-ene-3,20-dione), is a C21 steroid hormone involved in the female menstrual cycle, gestation and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens and is the major naturally occurring progestogen.
Progesterone is an essential regulator of human female reproductive function in the uterus, ovary, mammary gland and brain. It also plays important roles in non-reproductive tissues such as the cardiovascular, skeletal, and central nervous systems. Progesterone action is conveyed by two isoforms of the nuclear progesterone receptor (PR), PR-A and PR-B. PR-A and -B are expressed in a variety of normal and cancerous breast tissue cells from humans, rats and mice. Progesterone also has neurotrophic roles in the peripheral nervous system. It activates the growth and maturation of axons and stimulates the repair and replacement of myelin sheaths in regenerating nerve fibers.