Ceruloplasmin Colorimetric Activity Kit

Research Areas

Product Protocol Product SDS

Assay Type Activity Assay
Sample Types Serum, Urine
Sensitivity 3.26 mU/mL
Species Mammalian Species
Assay Duration 1 Hour
Samples/Plate 41 in Duplicate
Readout Colorimetric, 560 nm
Standard Curve
Description
Ceruloplasmin (Cp) is an acute phase multicopper oxidase enzyme that normally plays a protective role in responses to immune-provoking stimuli and is also associated with reproduction. Estrogens alter the subcellular distribution of copper in the liver, leading to an increase in plasma copper levels and subsequent ceruloplasmin synthesis. Serum levels of Cp have been shown to increase during normal pregnancy in some species, possibly as a protection against the oxidative costs of reproduction. In giant pandas and some felids, urinary Cp activity has shown to be elevated in pregnant vs. pseudopregnant animals beginning in the first week of gestation and continuing throughout the luteal phase.

The DetectX^® Ceruloplasmin Activity Kit quantitatively measures ceruloplasmin activity in serum and urine samples.

Assay Type Activity Assay
Sample Types Serum, Urine
Sensitivity 3.26 mU/mL
Species Mammalian Species
Assay Duration 1 Hour
Samples/Plate 41 in Duplicate
Readout Colorimetric, 560 nm
Standard Curve
Description
Ceruloplasmin (Cp) is an acute phase multicopper oxidase enzyme that normally plays a protective role in responses to immune-provoking stimuli and is also associated with reproduction. Estrogens alter the subcellular distribution of copper in the liver, leading to an increase in plasma copper levels and subsequent ceruloplasmin synthesis. Serum levels of Cp have been shown to increase during normal pregnancy in some species, possibly as a protection against the oxidative costs of reproduction. In giant pandas and some felids, urinary Cp activity has shown to be elevated in pregnant vs. pseudopregnant animals beginning in the first week of gestation and continuing throughout the luteal phase.