• Features Impairs prostate cancer cell growth
  • Inhibits the function of VCP
  • Cell permeable
  • Description

    Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II). Impairs prostate cancer cell growth and proliferation. Cell permeable.

  • Structure