Creatinine Serum Detection Kit

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Features

  • USE - Kidney Damage
  • SAMPLE - Serum and Plasma
  • SAMPLES/KIT - 91 or 187 in Duplicate
  • CALIBRATED - N-Cal Kit, NIST-Calibrated
  • STABILITY - Liquid 4°C Stable Reagents

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Multi Species and N-Cal Kit

Description

The DetectX® Serum Creatinine Kit measures creatinine in serum and plasma samples. A creatinine standard, calibrated to a NIST creatinine standard, is provided to generate a standard curve. The color generating reaction is initiated with the Creatinine Detection Reagent. The assay utilizes a kinetic absorbance method to overcome interference by colored compounds in the sample. The concentration of creatinine is calculated using the delta of the optical density readings at 1 and 30 minutes. We offer a free Excel worksheet for concentration calculations.

Creatinine is a metabolite of phosphocreatine (p-creatine), a high-energy phosphate that can be utilized by tissues for the production of ATP. Creatine either comes from the diet or synthesized from the amino acids arginine, glycine, and methionine. Creatine and p-creatine are converted non-enzymatically to the metabolite creatinine, which diffuses into the blood and is excreted by the kidneys. In vivo, this conversion appears to be irreversible and in vitro it is favored by higher temperatures and lower pH. Measuring serum creatinine is one of the most commonly used indicators of renal function. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons. A good indicator of kidney function is given by the creatinine clearance test. Creatinine clearance can be accurately calculated using serum creatinine concentration and taking into account the variables of sex, age, weight, and race.

Serum Creatinine Standard Curve

 

Data Reduction Template by MyAssays

Item Catalog # Price
Serum Creatinine Detection Kit, 2 PlateKB02-H1$210.00Inquire About This Product
Serum Creatinine Detection Kit, 4 PlateKB02-H2$345.00Inquire About This Product


Publications

Date Publication
Jun 01 2017 PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury
Mar 16 2017 Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat brain
Jun 03 2016 Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model
Mar 31 2016 Discovery of Potential Biomarkers with Dose- and Time-Dependence in Cisplatin-Induced Nephrotoxicity Using Metabolomics Integrated with a Principal Component-Based Area Calculation Strategy
Jan 27 2016 Early atherosclerosis aggravates renal microvascular loss and fibrosis in swine renal artery stenosis
Dec 09 2015 Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice
Sep 02 2015 Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy
Aug 06 2015 Composition for Preventing or Treating Kidney Disease Comprising Pyrazole Derivative
Dec 16 2014 The parasitic worm product, ES-62 targets MyD88-dependent effector mechanisms to suppress ANA production and proteinuria in MRL/Lpr mice
Dec 08 2014 Endothelial progenitor cell-derived extracellular vesicles protect from complment-mediated mesangial injury in expeirment anti-Thy1.1 glomerulonephritis
Nov 17 2014 Both PD-1 Ligands Protect the Kidney from Ischemia Reperfusion Injury
Oct 22 2014 Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine
Sep 11 2014 Therapeutic Benefits of Delayed Lithium Administration in the Neonatal Rat after Cerebral Hypoxia-Ischemia
Sep 02 2014 Treatment with the Matricellular Protein CCN3 (nov) Blocks and/or Reverses Fibrosis Development in Obesity with Diabetic Nephropathy
Jul 14 2014 Axl Tyrosine Kinase Protects against Tubulo-Interstitial Apoptosis and Progression of Renal Failure in a Murine Model of Chronic Kidney Disease and Hyperphosphataemia
May 01 2014 Integrin-linked kinase regulates tubular aquaporin-2 content and intracellular location: a link between the extracellular matrix and water reabsorption
Apr 04 2014 Aspirin-triggered Resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury
Jan 08 2014 Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation
Dec 26 2013 Patent: COMPOSITION FOR LUPUS NEPHRITIS AND METHODS OF MAKING AND USING THE SAME
Oct 31 2013 Laquinimod delays and suppresses nephritis in lupus-prone mice and affects both myeloid and lymphoid immune cells
Jan 16 2013 High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway
Oct 27 2012 Stem Cell Transplantation Increases Antioxidant Effects in Diabetic Mice
Sep 29 2012 Human umbilical cord blood-derived mesenchymal stem cells prevent diabetic renal injury through paracrine action
Jun 02 2012 Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma
Oct 23 2011 A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.

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