Specifications

  • Sample Extracted Serum, EDTA or Heparin Plasma, Urine, Saliva, Fecal Extracts, TCM
  • Sensitivity 1.84 pg/mL
  • Time to Answer Overnight
  • Samples/Kit 39 or 231 in Duplicate
  • Stability Liquid 4°C Stable Reagents
  • Readout Glow Luminescent
  • Standard Curve K052-C Standard Curve
  • Description

    Aldosterone is a mineralocorticoid first isolated by the husband and wife team of Simpson and Tait at University College, London. Aldosterone controls the sodium-potassium balance through unidirectional salt reabsorption in a variety of tissues and glands. Synthesized from cholesterol in the zona glomerulosa of the adrenal cortex, secretion is regulated through the renin-angiotensin system. Angiotensin II and potassium stimulate primary secretion by increasing the rate of production of the steroid. Peripheral aldosterone levels are dependent on age and body position. Aldosterone measurement is useful in the investigation of primary and secondary aldosteronism including vascular disease, salt depletion, potassium loading, cardiac failure with ascites, and pregnancy.