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Research Areas
Specifications
- Use Stress Marker in < 2μL Serum or Plasma
- Sample Serum, Plasma, Urine, Respiratory Vapor, TCM and Feather, Hair and Fecal Extracts
- Multi-Format Standard Range of 10,000–39.06 pg/mL or 5,000–19.53 pg/mL
- Sensitivity 20.9 pg/mL in 50 µL format, 17.5 pg/mL in 100µL format
- Validation Mice, Rats, Humans, Primates, Birds, Cats, Ungulates, Whale, Lizard
- Time to Answer 1.5 Hours
- Samples/Kit 37 or 229 in Duplicate
- Stability Liquid 4°C Stable Reagents
- Readout Colorimetric, 450 nm
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Standard Curve
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Description
Corticosterone (Kendall’s Compound ‘B’) is a glucocorticoid secreted by the cortex of the adrenal gland. It is produced in response to stimulation of the adrenal cortex by ACTH and is the precursor of aldosterone. Corticosterone is a major indicator of stress and is the major stress steroid produced in non-human mammals. Studies involving corticosterone and levels of stress have found evidence of impairment of long term memory retrieval, chronic corticosterone elevation due to dietary restrictions, and corticosterone elevation in response to burn injuries. In addition to stress levels, corticosterone is believed to play a decisive role in sleep-wake patterns.