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Specifications
- Assay Type Competitive ELISA
- Sample Types Serum, Plasma, Urine, and Fecal Extracts
- Sensitivity 2.97 pg/mL
- Species Testosterone is identical across all species
- Assay Duration 2.5 Hours
- Samples/Plate 38 in Duplicate
- Readout Colorimetric, 450 nm
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Standard Curve
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Description
Testosterone (4-Androsten-17β-ol-3-one) is an anabolic steroid hormone from the androgen group. It is found in mammals, reptiles, birds, and other vertebrates. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands. It is the principal male sex hormone and plays key roles in the development of reproductive tissues such as the testes and prostate, and in promoting secondary sexual characteristics such as increased muscle, bone mass, and body hair. In addition, testosterone is essential for health and well-being as well as the prevention of osteoporosis. Testosterone plays a significant role in glucose homeostasis and lipid metabolism. Cross-sectional epidemiological studies have reported a direct correlation between plasma testosterone and insulin sensitivity. Low testosterone levels are associated with an increased risk of type 2 diabetes, dramatically illustrated by androgen deprivation in men with prostate carcinoma.
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Structure