publications

Molecular basis of SLC19A1-mediated folate and cyclic dinucleotide transport

Published in 2025

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression

Published in 2024

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

BK Polyomavirus infection of bladder microvascular endothelial cells leads to the activation of the cGAS‐STING pathway

Published in 2024

Species

Human

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Immunomodulatory effects of trastuzumab deruxtecan through the cGAS-STING pathway in gastric cancer cells

Published in 2024

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Inhibiting the cGAS-STING pathway in myeloid cells effectively improves myocardial healing related to TET2 deficiency-induced DNA damage response

Published in 2024

Species

Mouse

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

Published in 2023

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Computational design of constitutively active cGAS

Published in 2023

Species

Bacteria

Sample

Cell Culture

Featured Products

2′,3′-Cyclic GAMP ELISA Kit , 3′,3′-Cyclic GAMP ELISA Kit

Tight nuclear tethering of cGAS is essential for preventing autoreactivity

Published in 2019

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Human DNA-PK activates a STING-independent DNA sensing pathway

Published in 2020

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells

Published in 2020

Species

Mouse

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis

Published in 2022

Species

Allium

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

Published in 2022

Species

Mouse

Sample

Supernatant

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease

Published in 2023

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

cGAS exacerbates Schistosoma japonicum infection in a STING-type I IFN-dependent and independent manner

Published in 2022

Species

Worm

Sample

Supernatant

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

ER-directed TREX1 limits cGAS activation at micronuclei

Published in 2021

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

Published in 2023

Species

Human

Sample

Supernatant

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing

Published in 2021

Species

Bacteria

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP

Published in 2022

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Pseudomonas aeruginosa Induces Interferon-beta Production to Promote Intracellular Survival

Published in 2022

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

A G-quadruplex stabilizer, CX-5461 combined with two immune checkpoint inhibitors enhances in vivo therapeutic efficacy by increasing PD-L1 expression in colorectal cancer

Published in 2023

Species

Human, Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit