publications

Bacterial 2′,3′-cGAMP activates a SAVED effector to form membrane-disrupting filaments and restrict phage replication

Published in 2026

Species

Bacteria

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

An ultrasmall core-shell silica nanoparticle improves antitumour immunity and survival by remodelling suppressive melanoma microenvironments

Published in 2025

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Substrate recognition diversity and transport dynamics of ABCC1

Published in 2025

Species

Human

Sample

Cell Lysate, Supernatant

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

JPI-547, a Dual Inhibitor of PARP/tankyrase, Shows antitumor activity against pancreatic cancers with homologous recombination repair deficiency or Wnt-Addiction

Published in 2025

Species

Mouse

Sample

Serum

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Annexin A1 mRNA-loaded liposomes alleviate acute pancreatitis by suppressing STING pathway and promoting efferocytosis in macrophages

Published in 2025

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

ATM and ATR inhibition increases radiosensitivity and cGAS-STING activation in prostate cancer

Published in 2025

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

PCK1 inhibits cGAS-STING activation by consumption of GTP to promote tumor immune evasion

Published in 2025

Species

Bacteria

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

ADSL-generated fumarate binds and inhibits STING to promote tumour immune evasion

Published in 2025

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Molecular basis of SLC19A1-mediated folate and cyclic dinucleotide transport

Published in 2025

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression

Published in 2024

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

BK Polyomavirus infection of bladder microvascular endothelial cells leads to the activation of the cGAS‐STING pathway

Published in 2024

Species

Human

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Inhibiting the cGAS-STING pathway in myeloid cells effectively improves myocardial healing related to TET2 deficiency-induced DNA damage response

Published in 2024

Species

Mouse

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

Published in 2023

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Computational design of constitutively active cGAS

Published in 2023

Species

Bacteria

Sample

Cell Culture

Featured Products

2′,3′-Cyclic GAMP ELISA Kit , 3′,3′-Cyclic GAMP ELISA Kit

Tight nuclear tethering of cGAS is essential for preventing autoreactivity

Published in 2019

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Human DNA-PK activates a STING-independent DNA sensing pathway

Published in 2020

Species

Human

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells

Published in 2020

Species

Mouse

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis

Published in 2022

Species

Allium

Sample

Cell Lysate

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

Published in 2022

Species

Mouse

Sample

Supernatant

Featured Product

2′,3′-Cyclic GAMP ELISA Kit

Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease

Published in 2023

Species

Mouse

Sample

Cell Culture

Featured Product

2′,3′-Cyclic GAMP ELISA Kit