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Advances in Non-Invasive Hormone Monitoring

non-invasive hormone monitoring image with a mouse

Corticosterone & Non-Invasive Sample Types

Corticosterone—the most common glucocorticoid in rodent animal models of stress—is easily measured using ELISA techniques. However, blood sample collection procedures are inherently stressful, and non-invasive methods such as saliva and fecal samples are often preferred. As each species generates a variety of hormone metabolites in differing concentrations, it is important to validate each assay with the species to ensure that the assay usefully indicates physiology. For HPA-related hormones, the use of an ACTH challenge is often used.

A recent study by Andreas Eleftheriou, Rupert Palme and Rudy Boonstra investigated use of a general and a group-specific ELISA to assess stress levels in rodent models. Using a Corticosterone ELISA kit from Arbor Assays, the authors validated the immunoassays for measuring fecal corticosterone metabolites in a deer mouse model of stress.

Our Corticosterone ELISA and Chemiluminescent Assay Kits are the industry’s gold-standard with over 290 citations and counting in high-impact, peer-reviewed journal articles.

OUR IMPROVED, MULTI-FORMAT CORTICOSTERONE ELISA KIT (K014-H):

  • Multiple formats and added sensitivity without kit component changes:
    • 50 μL format from 10,000 to 39.06 pg/mL
    • 100 μL format from 5,000 to 19.53 pg/mL
  • Saliva samples now validated; no extraction required
  • Only small sample volumes required: as little as 2 μL!
  • Validated in multiple species
  • Over 290 citations in peer-reviewed journals
  • Guaranteed, long-lasting supply—ideal for long term studies

LEARN MORE

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