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Showing 17–25 of 25 results
Phenylbutyrate, Na Salt
Histone deacetylase inhibitor that displays anticancer activity. Inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. Also…
Piceatannol
Activator of human deacetylase SIRT1. Anti-inflammatory, immunomodulatory and antiproliferative agent that inhibits p56lck and syk protein tyrosine kinases and inhibits…
Resveratrol
Potent SIRT1 activator and a phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 =…
SAHA (Vorinostat)
SAHA (suberoylanilide hydroxamic acid, Vorinostat, Zolinza™) is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of…
Sirtinol
Cell-permeable, selective sirtuin deacetylase inhibitor (IC50 values are 38, 68 and 131 uM for SIRT2, Sir2p and SIRT1 respectively) that…
Sodium Valproate
An anticonvulsant used in the treatment of epilepsy, anorexia nervosa, panic attack, anxiety disorder, post traumatic stress disorder, migraine and…
Tranylcypromine
Inhibitor of prostacyclin synthase1, monoamine oxidase inhibitor. Also an inhibitor of LSD1, a histone H3 demethylase (IC50>2uM). Treatment of P19…
Trichostatin A
Trichostatin A is a potent, reversible inhibitor of histone deacetylase (HDAC) with a Ki of 3.4 nM. In human Jurkat…
Xanthohumol
Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of…