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What Makes Cortisol Different Among Species?

STUMPED?
The molecules, of course, are 100% identical. The structure of the cortisol molecule is exactly the same regardless of the species or sample where it’s found.

Q: SO, WHY ARE THERE SO MANY SPECIES-SPECIFIC CORTISOL ASSAYS ON THE MARKET?

A: BECAUSE THEY DON’T KNOW STEROIDS LIKE WE DO. One producer will often supply more than a dozen different kits to measure cortisol, each assigned to a different species.  It is unusual to make species specific ELISA kits for “small molecules” because biomarkers like cortisol are absolutely identical throughout the animal kingdom. Understandably, this unconventional kit labeling can cause concern among researchers who study multiple species.

Q: DO YOU NEED TO USE DIFFERENT CORTISOL ASSAYS DEPENDING ON THE ANIMAL MODEL SYSTEM?

A: NO. ARBOR ASSAYS’ CORTISOL ELISA KIT (K003-H1/H5) HAS BEEN VALIDATED IN DOZENS OF SPECIES. These include fish, monkeys, humans, whales, and most recently in Aceh Cattle from Indonesia.  Our assay kits are developed and built with the absolute highest standards to meet the specificity, sensitivity, and assay reproducibility challenges researchers require. When only the best research tools will do, look to Arbor Assays.

 

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