The Use of Normalization Assays
...a reference molecule for the normalization of assays carried out on red blood cells (RBCs), serum and plasma samples. Many enzymes or other molecules assessed in RBCs are reported per...
News & Blog
Oxidative Stress, Copper, and Glutathione
...optimal cellular viability. Cu is required for proper function of a variety of important enzymes, such as cytochrome c oxidase, ceruloplasmin, and Cu/Zn superoxide dismutase. However, excessive free Cu ions...
Post-Stroke Dementia Biomarkers
...processes after stroke, and ACh levels are significantly lower in cerebrospinal fluid in patients with small-vessel vascular dementia. This suggests that cholinergic agents or cholinesterase inhibitors, both of which increase...
Endothelin-1: A Potent Vasoconstrictor
...our new Endothelin-1 (ET-1) ELISA Kit Our New Endothelin-1 (ET-1) Enzyme Immunoassay Kit (K045-H1), is the world’s most sensitive ET-1 kit. It is designed to quantitatively measure ET-1 present in...
Oxytocin: The “Love Hormone”
...Immunoassay (K048-C1/C5), breaks the 10 pg/mL barrier, and along with the Oxytocin Enzyme Immunoassay (K048-H1/H5), offers reproducible, reliable, affordable, consistent and quantitative detection of oxytocin, mesotocin, and isotocin. After an...
Non-Invasive Pregnancy Analysis
...the corticosteroids, androgens and estrogens. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, and from 17-hydroxypregnenolone via 3ß-hydroxysteroid dehydrogenase 2/Δ5-4 isomerase. It is then hydroxylated at positions 11...
Thyroxine EIA – Ideal for Metabolomics
...and deiodination to produce iodothyronamine and thyronamine. Because all three isoforms of the deiodinases are selenium-containing enzymes, dietary selenium is essential for T3 production. Hypothyroidism is the condition that results...
Ceruloplasmin Activity in Urine and Serum
...of the sera. The Arbor Assays Ceruloplasmin Colorimetric Activity kit, K035-H1, is exclusively licensed from Memphis Zoo and is a convenient method to measure the activity of this enzyme in...
Aldosterone: Monitoring the Regulation of Blood Pressure
...that interfere with the secretion or function of aldosterone are in clinical use as antihypertensives. For example, Lisinopril blocks the action of angiotensin-converting enzyme, reducing aldosterone secretion. The treatment goal...
Adapting to Climate Change
...enzymes Superoxide Dismutase (SOD, Arbor Assays Cat.# K028-H1) and Catalase (Arbor Assays Cat.# K033-H1). Across their range of treatment conditions with 3 and 6 month exposure they found no change...
Oxidative Cost of Reproduction
...differences were observed between pregnant and non-pregnant snakes regardless of water variability. -Glutathione peroxidase and superoxide dismutase activities are indicators of the function of anti-oxidant scavenging enzyme cascades within the...
Oxidative Stress as a Result of Acute Hypoxia
Under normal cellular conditions there is a constant balancing act between the creation of reactive oxygen species (ROS) and their elimination by the antioxidant system including enzymes such as superoxide...
Effects of Oxidative Stress on Germination
...demonstrated the increase in ROS during seed storage may ultimately be linked to a decrease in function of antioxidant enzymes, and once the imbalance forms, the excess ROS can cause...
Oxidative Stress After Hypoxia
Under normal cellular conditions there is a constant balancing act between the creation of reactive oxygen species (ROS) and their elimination by the antioxidant system including enzymes such as superoxide...