Search Results for: enzyme inhibitors and activators

…curve. Background: Acetylcholinesterase (AChE) is an enzyme critical for breaking down Acetylcholine (ACh). ACh is a key neurotransmitter in cholinergic neurons within the central and peripheral nervous systems. Enzyme AChE…

…in substrate specificity and catalytic activity. These enzymes metabolize a wide range of exogenous and endogenous compounds, participating in multicomponent electron transfer reactions. In toxicology, cytochrome P450 enzymes are of…

…dismutases (SODs) are key enzymes in the body’s antioxidant defense system, scavenging harmful oxygen species such as superoxide (O2-·), hydroxyl radical (·OH), and hydrogen peroxide (H2O2). These enzymes, including copper-zinc…

Assay Principle: The DetectX® Histone Demethylase (HDM) Fluorescent Activity Kit provides an efficient and precise method to measure HDM activity in lysates and purified enzyme systems. The kit has a…

…Catalase, an enzyme encoded by a single gene and highly conserved across species, efficiently eliminates peroxide. All tissues in mammals, including humans and mice, express catalase, with high concentrations found…

…and eukaryotic cells. Catalase, an enzyme encoded by a single gene and highly conserved across species, efficiently eliminates peroxide. All tissues in mammals, including humans and mice, express catalase, with…

…robustly to adrenaline. The enzyme phosphodiesterase catalyzes the decomposition of cAMP into AMP. Cyclic AMP’s broad role in cellular signaling and regulation is reflected in the Human Metabolome Database, which…

…to adrenaline. The enzyme phosphodiesterase catalyzes the decomposition of cAMP into AMP. The Human Metabolome Database reflects Cyclic AMP’s broad role in cellular signaling and regulation, listing 166 metabolic enzymes…

…The transformation of dehydroepiandrosterone (DHEA) to DHEA-S requires sulfation, catalyzed by sulfotransferase enzymes SULT1A1 and SULT1E1. These enzymes also produce estrone sulfate from estrone. Despite having a 17-ketone group instead…

…four times more potent than T4) within cells via deiodinase enzymes. All three deiodinase isoforms are selenium-containing enzymes; thus, dietary selenium is essential for T3 production. Hypothyroidism results from the…

…high plasma BChE activity, in contrast to rats, which have higher acetylcholinesterase activity in plasma. Cholinesterase inhibitors, which act on both AChE and BChE, play an important role in preserving…

…hydroxylation at the 11 and 21 positions to form cortisol. Deficiencies in enzymes like 11- or 21-hydroxylase lead to reduced cortisol synthesis, disrupting the feedback inhibition of adrenocorticotropic hormone (ACTH)….

…in transcription and enzyme activity. Notably, bacterial riboswitches, which are gene-regulatory RNA elements, bind cGAMP with high specificity, influencing genes related to motility, biofilm formation, colonization, and virulence. This functionality…

…560nm. Calculate Ceruloplasmin activity using the intensity and the standard curve. Background: Ceruloplasmin (Cp) is a multifaceted acute phase multicopper oxidase enzyme that plays a protective role in immune responses….